武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Aprataxin Rabbit mAb

Anti-Aprataxin Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N261862

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261862
产品全名:   Aprataxin 兔单克隆抗体
基因符号   AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
UNIPROT ID:   Q7Z2E3
背景:   DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5′-phosphate termini, resulting in the production of 5′-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5′-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3′-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5′-linked adenosine (AppDNA) .
抗原:   A synthetic peptide of human Aprataxin
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R03-9F6
分子量:   Calculated MW: 41 kDa; Observed MW: 41 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Aprataxin in K562, Hela lysates using Aprataxin antibody.

Immunocytochemistry analysis of Aprataxin (green) in U87-MG using Aprataxin antibody,and DAPI(blue).
           引用文献