武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

APC Rabbit mAb

Anti-APC Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263222

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263222
产品全名:   APC 兔单克隆抗体
基因符号   APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
UNIPROT ID:   P25054
背景:   Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
抗原:   A synthetic peptide of human APC
经过测试的应用:   WB,ICC/IF,IP
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R06-2E4
分子量:   Calculated MW: 312 kDa; Observed MW: 160 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of APC in Hela, A549, HL-60, U2OS lysates using APC antibody.

Immunocytochemistry analysis of APC (green) in LNcap using APC antibody,and DAPI(blue).
           引用文献