武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ALOX5 Rabbit pAb

Anti-ALOX5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216243

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216243
产品全名:   ALOX5 兔多抗
基因符号   5-LO, 5LPG, LOG5, 5-LOX
UNIPROT ID:   P09917 (Gene Accession – BC130332 )
背景:   This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原:   Fusion protein of human ALOX5
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 500-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cancer, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 216243(ALOX5 Antibody) at a dilution of 1/25(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer tissue using 216243(Anti-ALOX5 Antibody) at a dilution of 1/25.
           引用文献