武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ALK Rabbit pAb

Anti-ALK Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219631

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219631
产品全名:   ALK 兔多抗
基因符号   CD246, NBLST3
UNIPROT ID:   Q9UM73 (Gene Accession – NP_004295 )
背景:   This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).
抗原:   Synthetic peptide of human ALK
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 1000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human cervical cancer tissue using 219631(ALK Antibody) at a dilution of 1/25(Cell membrane, Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 219631(Anti-ALK Antibody) at a dilution of 1/25.
           引用文献