武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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AIM2 Rabbit pAb

Anti-AIM2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S210945

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S210945
产品全名:   AIM2 兔多抗
基因符号   PYHIN4
UNIPROT ID:   O14862 (Gene Accession – BC010940 )
背景:   Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-?, AIM2 is thought to act as a tumor suppressor by repressing NF?B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of †-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
抗原:   Fusion protein of human AIM2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 1000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 210945(AIM2 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 210945(Anti-AIM2 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 210945(Anti-AIM2 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D121935(Anti-AIM2 Antibody) at dilution 1/60.
           引用文献