武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ACTN2 Rabbit pAb

Anti-ACTN2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S220877

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S220877
产品全名:   ACTN2 兔多抗
基因符号   MPD6; CMH23; CMD1AA; MYOCOZ
UNIPROT ID:   P35609 (Gene Accession – NP_001094 )
背景:   Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
抗原:   Synthetic peptide of human ACTN2
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 1000-5000;ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human skeletal muscle tissue using 220877(ACTN2 Antibody) at a dilution of 1/50(Cytoplasm).

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart and muscle tissue;
Primary antibody: 220877(ACTN2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
           引用文献