武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ABCB4 Rabbit pAb

Anti-ABCB4 Rabbit Polyclonal Antibody
5/5

$2,850.00

货号:S221299

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221299
产品全名:   ABCB4 兔多抗
基因符号   GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3
UNIPROT ID:   P21439 (Gene Accession – NP_000434 )
背景:   The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
抗原:   Synthetic peptide of human ABCB4
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221299(ABCB4 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221299(Anti-ABCB4 Antibody) at dilution 1/70.
           引用文献