武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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HP1 gamma Rabbit mAb

Anti-HP1 gamma Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262358

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262358
产品全名:   HP1 gamma 兔单克隆抗体
基因符号   HECH; HP1-GAMMA; HP1Hs-gamma; CBX3
UNIPROT ID:   P23198
背景:   Component of heterochromatin. Recognizes and binds histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ‘Lys-9’ trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
抗原:   A synthetic peptide of mouse HP1 gamma
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R02-8A2
分子量:   Calculated MW: 21 kDa; Observed MW: 21 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HP1 gamma antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of HP1 gamma in K562, C6, 3T3 lysates using HP1 gamma antibody.
           引用文献