武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GNA13 Rabbit mAb

Anti-GNA13 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262249

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262249
产品全名:   GNA13 兔单克隆抗体
基因符号   guanine nucleotide binding protein (G protein); alpha 13; G13
UNIPROT ID:   Q14344
背景:   Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) . Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).
抗原:   A synthetic peptide of human G protein alpha 13
经过测试的应用:   WB,IHC-P
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R08-4F2
分子量:   Calculated MW: 44 kDa; Observed MW: 44 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using G protein alpha 13 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of GNA13 [KO Validated] in Hela, Jurkat lysates using GNA13 antibody.
           引用文献