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IL-17 Receptor C Rabbit pAb

Anti-IL-17 Receptor C Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225452

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225452
产品全名:   IL-17 Receptor C 兔多抗
基因符号   IL17RC; Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14
UNIPROT ID:   Q8NAC3
背景:   This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
抗原:   The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770
经过测试的应用:   WB,ELISA
推荐稀释比:   WB: 1/500-1/1000 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 86 kDa; Observed MW: 70 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IL-17 Receptor C in RAW264.7 lysates using IL-17RC antibody.

Western blot analysis of IL-17 Receptor C in various lysates using IL-17 Receptor C antibody.

Western blot analysis of IL-17 Receptor C in HuvEc lysates using IL-17RC antibody.
           引用文献