武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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IGF1 Receptor Rabbit pAb

Anti-IGF1 Receptor Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225286

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225286
产品全名:   IGF1 Receptor 兔多抗
基因符号   IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
UNIPROT ID:   P08069
背景:   This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
抗原:   Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
经过测试的应用:   WB,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 155 kDa; Observed MW: 95,200 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of IGF1 Receptor in MCF using IGF1 Receptor antibody.

Western blot analysis of IGF1 Receptor in 293 lysates usingIGF1 Receptor antibody. and the same antibody. preincubated with blocking peptide.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using IGF1 Receptor antibody(left) or the same antibody preincubated with blocking peptide (right).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
           引用文献