武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CD135 Rabbit pAb

Anti-CD135 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225195

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225195
产品全名:   CD135 兔多抗
基因符号   FLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135
UNIPROT ID:   P36888
背景:   This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
抗原:   The antiserum was produced against synthesized peptide derived from the Internal region of human FLT3. AA range:451-500
经过测试的应用:   WB,ELISA
推荐稀释比:   WB: 1/500-1/1000 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 113 kDa; Observed MW: 110 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of CD135 in 4T1 lysates using CD135 antibody.
           引用文献