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PINCH (3C12) Mouse mAb

Anti-PINCH (3C12) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261198

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261198
产品全名:   PINCH (3C12) 小鼠单抗
基因符号   LIMS1; PINCH; PINCH1; LIM and senescent cell antigen-like-containing domain protein 1; Particularly interesting new Cys-His protein 1; PINCH-1; Renal carcinoma antigen NY-REN-48
UNIPROT ID:   P48059
背景:   The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
抗原:   Purified recombinant fragment of human PINCH expressed in E. Coli.
经过测试的应用:   WB,ICC/IF,FC,IP
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   3C12-F7-A8
分子量:   Calculated MW: 37 kDa; Observed MW: 37 kDa
亚型:   IgG1
纯化:   Ascitic Fluid
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of PINCH (3C12) in HepG2 cells using PINCH (3C12) antibody (green)and DAPI (blue).

Immunoprecipitation analysis of PINCH in Hela lysates using PINCH antibody.

Western blot analysis of PINCH (3C12) in C6, Jurkat, K562, 3T3 and Hela lysates using PINCH (3C12) antibody

Flow cytometry analysis of Hela stained with PINCH antibody (blue) and negative control (red).
           引用文献