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Smad5 (4B10) Mouse mAb

Anti-Smad5 (4B10) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261030

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261030
产品全名:   Smad5 (4B10) 小鼠单抗
基因符号   DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad 5; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD; mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; Smad5; Smad5; SMAD5_HUMAN.
UNIPROT ID:   Q99717
背景:   Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. Smad5 is a receptor-regulated Smad (R-Smad). Smad5 is required for normal development of the cardiovascular system in vivo; lack of the Smad5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of Smad5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
抗原:   Purified recombinant human SMAD5 (C-terminus) protein fragments expressed in E.coli.
经过测试的应用:   WB,ICC/IF,FC
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   4B10-B10-B6
分子量:   Calculated MW: 52 kDa; Observed MW: 60 kDa
亚型:   IgG1
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Smad5 in HeLa cells using Smad5 antibody.

Western blot analysis of SMAD5 (Cterminus) in Hela, Jurkat and K562 lysates using SMAD5 (Cterminus) antibody.

Flow Cytometry analysis of Jurkat cells stained with SMAD5 (red). Black line histogram represents the isotype control, normal mouse IgG.
           引用文献