武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CTSD Rabbit pAb

Anti-CTSD Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222406

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222406
产品全名:   CTSD 兔多抗
基因符号   CPSD; CLN10; HEL-S-130P
UNIPROT ID:   P07339 (Gene Accession – NP_001900 )
背景:   This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer’s disease.
抗原:   Synthetic peptide of human CTSD
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-100;WB: 1000-5000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cell Biology, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 222406(CTSD Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 222406(Anti-CTSD Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: MCF-7 cell lysate;
Primary antibody: 222406(CTSD Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
           引用文献