武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CLDN6 Rabbit pAb

Anti-CLDN6 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222380

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222380
产品全名:   CLDN6 兔多抗
基因符号   
UNIPROT ID:   P56747 (Gene Accession – NP_067018 )
背景:   Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
抗原:   Synthetic peptide of human CLDN6
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222380(CLDN6 Antibody) at a dilution of 1/55(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222380(Anti-CLDN6 Antibody) at dilution 1/55.
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