| 货号: S222199 |
| 产品全名: HOXD4 兔多抗 |
| 基因符号 HOX4; HOX4B; HHO.C13; HOX-5.1; Hox-4.2 |
| UNIPROT ID: P09016 (Gene Accession – NP_055436 ) |
| 背景: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5′ end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. |
| 抗原: Synthetic peptide of human HOXD4 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: Oct-50; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222199(HOXD4 Antibody) at a dilution of 1/25(Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222199(Anti-HOXD4 Antibody) at dilution 1/25. | 
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 222199(Anti-HOXD4 Antibody) at a dilution of 1/25. | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D264212(Anti-HOXD4 Antibody) at dilution 1/25. |
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