武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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HLA-DOB Rabbit pAb

Anti-HLA-DOB Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222184

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222184
产品全名:   HLA-DOB 兔多抗
基因符号   DOB; HLA_DOB
UNIPROT ID:   P13765 (Gene Accession – NP_002111 )
背景:   HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
抗原:   Synthetic peptide of human HLA-DOB
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 222184(HLA-DOB Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 222184(Anti-HLA-DOB Antibody) at dilution 1/45.
           引用文献