武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DUX4 Rabbit pAb

Anti-DUX4 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221926

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221926
产品全名:   DUX4 兔多抗
基因符号   DUX4L
UNIPROT ID:   Q9UBX2 (Gene Accession – NP_001280727 )
背景:   This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.
抗原:   Synthetic peptide of human DUX4
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Stem Cells
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221926(DUX4 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221926(Anti-DUX4 Antibody) at dilution 1/30.
           引用文献