| 货号: S221079 |
| 产品全名: UCP2 兔多抗 |
| 基因符号 UCPH; BMIQ4; SLC25A8 |
| UNIPROT ID: P55851 (Gene Accession – NP_003346 ) |
| 背景: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5′-UCP3-UCP2-3′. |
| 抗原: Synthetic peptide of human UCP2 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 200-1000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer, Metabolism |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 221079(UCP2 Antibody) at a dilution of 1/20(Cytoplasm). | 
Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer tissue using 221079(Anti-UCP2 Antibody) at a dilution of 1/20. | 
Gel: 8%SDS-PAGE, Lysate: 60 μg;
Lane: Mouse liver tissue lysate;
Primary antibody: 221079(UCP2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes | |
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