武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MAP3K11 Rabbit pAb

Anti-MAP3K11 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S220716

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S220716
产品全名:   MAP3K11 兔多抗
基因符号   MLK3; PTK1; SPRK; MLK-3; MEKK11
UNIPROT ID:   Q16584 (Gene Accession – NP_002410 )
背景:   The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
抗原:   Synthetic peptide of human MAP3K11
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220716(MAP3K11 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220716(Anti-MAP3K11 Antibody) at dilution 1/50.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: K562, NIH/3T3, PC3, LO2, MCF7 cell lysates;
Primary antibody: 220716(MAP3K11 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 20 seconds
           引用文献