武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GCH1 Rabbit pAb

Anti-GCH1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219841

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219841
产品全名:   GCH1 兔多抗
基因符号   GCH, DYT5, DYT14, DYT5a, GTPCH1, HPABH4B, GTP-CH-1
UNIPROT ID:   P30793 (Gene Accession – NP_001019242 )
背景:   This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
抗原:   Synthetic peptide of human GCH1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 20-May;WB: 500-2000;ELISA: 1000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Signal Transduction, Cell Biology, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219841(GCH1 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219841(Anti-GCH1 Antibody) at dilution 1/15.

Gel: 12%SDS-PAGE, Lysate: 60 μg;
Lane: Human fetal liver tissue;
Primary antibody: 219841(GCH1 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 15 seconds
           引用文献