武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GRB10 Rabbit pAb

Anti-GRB10 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219829

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219829
产品全名:   GRB10 兔多抗
基因符号   RSS, IRBP, MEG1, GRB-IR, Grb-10
UNIPROT ID:   Q13322 (Gene Accession – NP_005302 )
背景:   The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.
抗原:   Synthetic peptide of human GRB10
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 1000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219829(GRB10 Antibody) at a dilution of 1/25(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219829(Anti-GRB10 Antibody) at dilution 1/25.
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