| 货号: S219418 |
| 产品全名: FKBP3 兔多抗 |
| 基因符号 FKBP-3; FKBP25; PPIase; FKBP-25 |
| UNIPROT ID: Q00688 (Gene Accession – BC016288 ) |
| 背景: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
| 抗原: Fusion protein of human FKBP3 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 200-300;WB: 1000-5000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219418(FKBP3 Antibody) at a dilution of 1/180(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219418(Anti-FKBP3 Antibody) at dilution 1/180. | 
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 219418(Anti-FKBP3 Antibody) at a dilution of 1/180. | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D226836(Anti-FKBP3 Antibody) at dilution 1/180. | 
Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human bladder transitional cell carcinoma cancer next level 2-3 tissue, Human bladder transitional cell carcinoma grade 2-3 tissue lysates;
Primary antibody: 219418(FKBP3 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds | |
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