| 货号: S219368 |
| 产品全名: SAV1 兔多抗 |
| 基因符号 SAV; WW45; WWP4 |
| UNIPROT ID: Q9H4B6 (Gene Accession – BC020537 ) |
| 背景: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. |
| 抗原: Fusion protein of human SAV1 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 100-300;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human brain tissue using 219368(SAV1 Antibody) at a dilution of 1/90(Cytoplasm or Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 219368(Anti-SAV1 Antibody) at dilution 1/90. | 
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 219368(Anti-SAV1 Antibody) at a dilution of 1/90. | 
In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D226556(Anti-SAV1 Antibody) at dilution 1/90. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: HUVEC, PC-3 cell lysates;
Primary antibody: 219368(SAV1 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute | |
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