武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CLCN7 Rabbit pAb

Anti-CLCN7 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218507

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218507
产品全名:   CLCN7 兔多抗
基因符号   HOD; CLC7; CLC-7; OPTA2; OPTB4; PPP1R63
UNIPROT ID:   P51798 (Gene Accession – BC012737 )
背景:   The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
抗原:   Fusion protein of human CLCN7
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218507(CLCN7 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218507(Anti-CLCN7 Antibody) at dilution 1/100.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HepG2, A549, LOVO cell lysates;
Primary antibody: 218507(CLCN7 Antibody) at dilution 1/500;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
           引用文献