武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CYP17A1 Rabbit pAb

Anti-CYP17A1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217326

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217326
产品全名:   CYP17A1 兔多抗
基因符号   CPT7; CYP17; S17AH; P450C17
UNIPROT ID:   P05093 (Gene Accession – BC063388 )
背景:   This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
抗原:   Fusion protein of human CYP17A1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Signal Transduction, Cancer, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217326(CYP17A1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217326(Anti-CYP17A1 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 217326(Anti-CYP17A1 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D222184(Anti-CYP17A1 Antibody) at dilution 1/20.
           引用文献