武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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PTCH1 Rabbit pAb

Anti-PTCH1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216755

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216755
产品全名:   PTCH1 兔多抗
基因符号   PTC; BCNS; PTC1; PTCH; NBCCS
UNIPROT ID:   Q13635 (Gene Accession – BC043542 )
背景:   This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly.
抗原:   Fusion protein of human PTCH1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Neuroscience, Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 216755(PTCH1 Antibody) at a dilution of 1/70(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using 216755(Anti-PTCH1 Antibody) at a dilution of 1/70.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse brain tissue lysate;
Primary antibody: 216755(PTCH1 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 20 seconds
           引用文献