| 货号: S216743 |
| 产品全名: PRCP 兔多抗 |
| 基因符号 PCP; HUMPCP |
| UNIPROT ID: P42785 (Gene Accession – BC001500 ) |
| 背景: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| 抗原: Fusion protein of human PRCP |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 200-1000;ELISA: 1000-2000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cell Biology, Cardiovascular |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216743(PRCP Antibody) at a dilution of 1/15(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216743(Anti-PRCP Antibody) at dilution 1/15. | 
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 216743(Anti-PRCP Antibody) at a dilution of 1/15. | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with fusion protein and then with D221156(Anti-PRCP Antibody) at dilution 1/15. | 
Gel: 10%SDS-PAGE, Lysate: 50 μg;
Lane 1-3: SKOV3 cells, A549 cells, human liver cancer tissue;
Primary antibody: 216743(PRCP Antibody) at dilution 1/100;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes | |
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