| 货号: S216607 |
| 产品全名: KLK7 兔多抗 |
| 基因符号 hK7, SCCE, PRSS6 |
| UNIPROT ID: P49862 (Gene Accession – BC032005 ) |
| 背景: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. |
| 抗原: Fusion protein of human KLK7 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 500-2000;ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216607(KLK7 Antibody) at a dilution of 1/10(Cytoplasm, Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216607(Anti-KLK7 Antibody) at dilution 1/10. | 
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 216607(Anti-KLK7 Antibody) at a dilution of 1/10. | 
In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D220906(Anti-KLK7 Antibody) at dilution 1/10. | 
Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse brain tissue, Mouse kidney tissue;
Primary antibody: 216607(KLK7 Antibody) at dilution 1/600;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds | |
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