武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DUSP6 Rabbit pAb

Anti-DUSP6 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216499

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216499
产品全名:   DUSP6 兔多抗
基因符号   MKP3, PYST1
UNIPROT ID:   Q16828 (Gene Accession – BC005047 )
背景:   The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
抗原:   Fusion protein of human DUSP6
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 1000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 216499(DUSP6 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 216499(Anti-DUSP6 Antibody) at dilution 1/50.
           引用文献