武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DUSP22 Rabbit pAb

Anti-DUSP22 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216496

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216496
产品全名:   DUSP22 兔多抗
基因符号   VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2
UNIPROT ID:   Q9NRW4 (Gene Accession – BC016844 )
背景:   Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
抗原:   Fusion protein of human DUSP22
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 216496(DUSP22 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 216496(Anti-DUSP22 Antibody) at dilution 1/60.
           引用文献