| 货号: S214201 |
| 产品全名: CADM4 兔多抗 |
| 基因符号 NECL4; TSLL2; IGSF4C; Necl-4; synCAM4 |
| UNIPROT ID: Q8NFZ8 (Gene Accession – NP_660339 ) |
| 背景: IGSF4C (immunoglobulin superfamily member 4C), also known as CADM4 (cell adhesion molecule 4), NECL4 or TSLL2, is a 388 amino acid single-pass type I membrane protein that contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed in kidney, brain and prostate, IGSF4C exists as both a monomer and a homodimer and is thought to be involved in cell-cell adhesion, possibly playing a role in tumor suppression. Human IGSF4C shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding IGSF4C maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs) |
| 抗原: Synthetic peptide of human CADM4 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 200-1000;ELISA: 1000-2000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214201(CADM4 Antibody) at a dilution of 1/25(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214201(Anti-CADM4 Antibody) at dilution 1/25. | 
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 214201(Anti-CADM4 Antibody) at a dilution of 1/25. | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D161503(Anti-CADM4 Antibody) at dilution 1/25. | 
Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: RAW264.7 cells, mouse brain tissue;
Primary antibody: 214201(CADM4 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds | |
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