武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TEAD2 Rabbit pAb

Anti-TEAD2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S212411

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S212411
产品全名:   TEAD2 兔多抗
基因符号   ETF; TEF4; TEF-4; TEAD-2
UNIPROT ID:   Q15562 (Gene Accession – BC007556 )
背景:   Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC ‘enhansons’ (5′-GTGGAATGT-3′). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
抗原:   Fusion protein of human TEAD2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer tissue using 212411(TEAD2 Antibody) at a dilution of 1/60(Nucleus).
           引用文献