武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RRM1 Rabbit pAb

Anti-RRM1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S210551

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S210551
产品全名:   RRM1 兔多抗
基因符号   R1; RR1; RIR1
UNIPROT ID:   P23921 (Gene Accession – BC006498 )
背景:   This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
抗原:   Fusion protein of human RRM1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 210551(RRM1 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 210551(Anti-RRM1 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 210551(Anti-RRM1 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D121160(Anti-RRM1 Antibody) at dilution 1/15.

Gel: 10%SDS-PAGE, Lysate: 50 μg;
Lane 1-2: Hela cells, 231 cells;
Primary antibody: 210551(RRM1 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
           引用文献