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Human IL7RA Protein, hFc Tag

Recombinant Human IL7RA with C-terminal human Fc tag
5/5

¥445.00

货号:11621

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11621
产品全名:   人 IL7RA 蛋白
规格:   10/50/100 µg
基因符号   CD127;CDW127;IL-7R-alpha;IL7RA;ILRA
目标蛋白:    IL7RA
UNIPROT ID:    P16871
描述:   Recombinant Human IL7RA with C-terminal human Fc tag
背景:     The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is approximately 55-100 kDa due to glycosylation.
分子特征:   IL7RA(Glu21-Gly236) hFc(Glu99-Ala330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL7RA Protein, hFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human IL7RA Protein, hFc Tag(11621) can bind Anti-IL7RA antibody(DMC272), IgG1 Chimeric mAb in a linear range of 3.20-80 ng/mL.
           引用文献