| 货号: 11216 |
| 产品全名: 人 ROR2 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 ROR2;TRKR2 |
| 目标蛋白: ROR2 |
| UNIPROT ID: Q01974 |
| 描述: Recombinant human ROR2 Protein with C-terminal 6xHis tag |
| 背景: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of ROR2-His is approximately 55-70 kDa due to glycosylation. |
| 分子特征: ROR2(Glu34-Gly403) 6×His tag |
| 纯化: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human ROR2 Protein, His Tag on SDS-PAGE under reducing condition. | 
Figure 2. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human ROR2 protein, His Tag (11216) can bind Anti-ROR2 Rabbit mAb in a linear range of 0.128-16 ng/mL. |
|
