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Human TIGIT Protein, mFc Tag

Recombinant human TIGIT Protein with C-terminal mouse Fc tag
5/5

¥445.00

货号:11308

规格: 100 μg

库存状态:In Stock

           产品描述          
货号:   11308
产品全名:   人 TIGIT 蛋白
规格:   10/50/100 µg
基因符号   TIGIT;SIG9;STM3
目标蛋白:    TIGIT
UNIPROT ID:    Q495A1
描述:   Recombinant human TIGIT Protein with C-terminal mouse Fc tag
背景:     This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
物种/宿主:    HEK293
分子量:   The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation.
分子特征:   TIGIT(Met22-Pro141) mFc(Pro99-Lys330)
纯化:   The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:   Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
储存和运输:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TIGIT Protein, mFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, mFc tagged protein (11308) can bind Anti-TIGIT Neutralizing antibody 28033 in a linear range of 0.13-16.0 ng/ml.
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