武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ZNF268 Rabbit pAb

Anti-ZNF268 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218049

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218049
产品全名:   ZNF268 兔多抗
基因符号   HZF3
UNIPROT ID:   Q14587 (Gene Accession – BC110542 )
背景:   Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.
抗原:   Fusion protein of human ZNF268
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-250; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218049(ZNF268 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218049(Anti-ZNF268 Antibody) at dilution 1/50.
           引用文献