武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TXNDC5 Rabbit pAb

Anti-TXNDC5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217963

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217963
产品全名:   TXNDC5 兔多抗
基因符号   HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI
UNIPROT ID:   Q8NBS9 (Gene Accession – BC052310 )
背景:   This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
抗原:   Fusion protein of human TXNDC5
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 200-400;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 217963(TXNDC5 Antibody) at a dilution of 1/180(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 217963(Anti-TXNDC5 Antibody) at dilution 1/180.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: HT29, 293T, Hela cell, Human placenta tissue lysates;
Primary antibody: 217963(TXNDC5 Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
           引用文献