武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TCF3 Rabbit pAb

Anti-TCF3 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217886

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217886
产品全名:   TCF3 兔多抗
基因符号   E2A; E47; p75; AGM8; ITF1; VDIR; AGM8A; AGM8B; TCF-3; bHLHb21
UNIPROT ID:   P15923 (Gene Accession – BC110580 )
背景:   This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
抗原:   Fusion protein of human TCF3
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217886(TCF3 Antibody) at a dilution of 1/80(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217886(Anti-TCF3 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 217886(Anti-TCF3 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D223301(Anti-TCF3 Antibody) at dilution 1/80.
           引用文献