武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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SETD7 Rabbit pAb

Anti-SETD7 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217505

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217505
产品全名:   SETD7 兔多抗
基因符号   KMT7; SET7; SET9; SET7/9
UNIPROT ID:   Q8WTS6 (Gene Accession – BC121055 )
背景:   The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule in an unusual conformation binds, a narrow substrate-specific channel that only unmethylated lysine residues can access and a catalytic tyrosine residue.
抗原:   Fusion protein of human SETD7
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217505(SETD7 Antibody) at a dilution of 1/20(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217505(Anti-SETD7 Antibody) at dilution 1/20.
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