武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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SEMA4D Rabbit pAb

Anti-SEMA4D Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217751

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217751
产品全名:   SEMA4D 兔多抗
基因符号   CD100; SEMAJ; coll-4; C9orf164; M-sema-G
UNIPROT ID:   Q92854 (Gene Accession – BC054500 )
背景:   Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
抗原:   Fusion protein of human SEMA4D
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Neuroscience, Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 217751(SEMA4D Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 217751(Anti-SEMA4D Antibody) at dilution 1/40.
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