武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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SEMA4A Rabbit pAb

Anti-SEMA4A Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217801

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217801
产品全名:   SEMA4A 兔多抗
基因符号   RP35; SEMB; SEMAB; CORD10
UNIPROT ID:   Q9H3S1 (Gene Accession – BC020974 )
背景:   This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
抗原:   Fusion protein of human SEMA4A
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Neuroscience, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217801(SEMA4A Antibody) at a dilution of 1/45(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217801(Anti-SEMA4A Antibody) at dilution 1/45.
           引用文献