武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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NECTIN4 Rabbit pAb

Anti-NECTIN4 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217644

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217644
产品全名:   NECTIN4 兔多抗
基因符号   LNIR; PRR4; EDSS1; PVRL4; nectin-4
UNIPROT ID:   Q96NY8 (Gene Accession – BC010423 )
背景:   This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
抗原:   Fusion protein of human NECTIN4
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217644(NECTIN4 Antibody) at a dilution of 1/60(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217644(Anti-NECTIN4 Antibody) at dilution 1/60.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: SKOV3 cell lysate;
Primary antibody: 217644(NECTIN4 Antibody) at dilution 1/550;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
           引用文献