武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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IL12B Rabbit pAb

Anti-IL12B Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222218

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222218
产品全名:   IL12B 兔多抗
基因符号   CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
UNIPROT ID:   P29460 (Gene Accession – NP_002178 )
背景:   This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
抗原:   Synthetic peptide of human IL12B
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: Oct-50; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 222218(IL12B Antibody) at a dilution of 1/25(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 222218(Anti-IL12B Antibody) at dilution 1/25.
           引用文献