武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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HIF1AN Rabbit pAb

Anti-HIF1AN Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218072

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218072
产品全名:   HIF1AN 兔多抗
基因符号   FIH1
UNIPROT ID:   Q9NWT6 (Gene Accession – BC007719 )
背景:   Hydroxylates HIF-1 alpha at ‘Asp-803’ in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively.
抗原:   Full length fusion 蛋白
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cardiovascular, Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 218072(HIF1AN Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 218072(Anti-HIF1AN Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 218072(Anti-HIF1AN Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D223653(Anti-HIF1AN Antibody) at dilution 1/25.
           引用文献