武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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HIF1A Rabbit pAb

Anti-HIF1A Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218073

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218073
产品全名:   HIF1A 兔多抗
基因符号   HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA
UNIPROT ID:   Q16665 (Gene Accession – BC012527 )
背景:   This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
抗原:   Fusion protein of human HIF1A
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cardiovascular, Epigenetics and Nuclear Signaling, Cancer, Metabolism
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 218073(HIF1A Antibody) at a dilution of 1/20(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 218073(Anti-HIF1A Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 218073(Anti-HIF1A Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D223656(Anti-HIF1A Antibody) at dilution 1/20.
           引用文献