武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GPM6A Rabbit pAb

Anti-GPM6A Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217143

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217143
产品全名:   GPM6A 兔多抗
基因符号   M6A; GPM6
UNIPROT ID:   P51674 (Gene Accession – BC022508 )
背景:   Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
抗原:   Fusion protein of human GPM6A
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 1000-5000;ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217143(GPM6A Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217143(Anti-GPM6A Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 217143(Anti-GPM6A Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221869(Anti-GPM6A Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 20 μg;
Lane: Human fetal brain tissue;
Primary antibody: 217143(GPM6A Antibody) at dilution 1/1050;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
           引用文献