武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DUSP11 Rabbit pAb

Anti-DUSP11 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217992

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217992
产品全名:   DUSP11 兔多抗
基因符号   PIR1
UNIPROT ID:   O75319 (Gene Accession – BC000346 )
背景:   The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
抗原:   Full length fusion 蛋白
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217992(DUSP11 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217992(Anti-DUSP11 Antibody) at dilution 1/50.
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